![]() Gepatrombin G - anti-hemorrhoidal drug for topical use with antithrombotic, anti-inflammatory and venosclerosis. Pharmacological properties Combined drug. Heparin - an anticoagulant of direct action, with external application has antithrombotic, antiexudative and moderate anti-inflammatory effect; promotes the regeneration of connective tissue, prevents coagulation of blood in the hemorrhoids. Prednisolone - glucocorticoid, has anti-inflammatory, antiexudative and anti-allergic effect; reduces inflammation and concomitant sensations (itching, burning, pain) in the anorectal area. Polidocanol has a local anesthetic effect and provides sclerosis of hemorrhoids. Indications for use Hepatrombin D External and internal. Do I need to take some precautions before using the drug 'Gepatrombin F'?Instructions for use recalls that people with individual intolerance to at least one of the components have to think about what they should refrain from taking this. Thrombophlebitis of the veins of the anus. Fistulas, eczema and itching in the anus. Cracks in the anus. Dosing and Administration Outwardly, the affected ointment is applied a thin layer 2-4 times a day; after the disappearance of pain - 1 time per day for 7 days. Rectally, suppositories are administered 1-2 times a day in the rectal cavity after defecation. For the introduction of the ointment, an attached screw-on tip is used, which is inserted into the rectal cavity, and a small amount of ointment is squeezed out by lightly pressing the tube. Application features When applying a large amount to damaged skin or mucous membranes, the regeneration process slows down. Side effects Allergic reactions. With long-term use and / or when applied to large surfaces, systemic side effects are possible. Contraindications Hypersensitivity; bacterial, viral, fungal skin lesions, tuberculosis, syphilis; skin tumors; pregnancy (I trimester); response to the introduction of vaccines; predisposition to bleeding. Information posted on the site can not be considered as a recommendation to patients for diagnosing and treating any diseases and can not serve as a substitute for consultation with a doctor. Nothing in this information should be interpreted as an appeal to non-specialists to independently treat diagnosed diseases. This information can not be used to make a decision to change the procedure and the regime of application of the recommendations of the attending physician. Copying materials is possible only with the placement of an active link to the source. Contacts: [email protected]. Ointment for rectal and external use yellowish white, translucent, gel-like. 1 g sodium heparin 65 IU * prednisolone acetate 2.233 mg laumromacrogol 600 30 mg Excipients: paraffin solid - 50 mg, paraffin liquid - 797.11 mg, lanolin - 50 mg, silicon dioxide colloid - 70 mg. 20 g - aluminum tubes (1) complete with a tip for rectal administration - packs cardboard. * 1 IU of sodium heparin - anticoagulant activity, corresponds to the activity of 7.7 μg of the II International Standard of Heparin (WHO). Pharmachologic effect. Combined drug with antithrombotic, anti-inflammatory and venosclerosis effect for topical application in proctology. Heparin is an anticoagulant of direct action. With external application has a local antithrombotic, antiexudative and moderate anti-inflammatory effect; promotes the regeneration of connective tissue; prevents coagulation of blood in the hemorrhoids. Prednisolone - GCS, has anti-inflammatory, antiexudative and antiallergic effect, reduces itching, burning sensation, pain in the anorectal area. Lauromacrogol 400 (polidocanol) has a local anesthetic effect and provides sclerosis of hemorrhoids. Heparin Absorption and Metabolism After absorption, biotransformed in the liver (partly by the hepatic enzyme heparinase enzyme) and in the reticuloendothelial system. Distribution and excretion Binding to plasma proteins is 95%. V d increases with increasing dose. It is excreted by the kidneys. T 1/2 - 60-90 min. Prednisolone Absorption and Metabolism Prednisolone after absorption is biotransformed in the liver. Excretion About 1% is excreted in the urine unchanged. The biological T 1/2 is 18-36 h, and T 1/2 of the plasma is 115-212 min. Consultations, express consultations and Information services render * Cost of consultation and information service - 499 rubles. The cost of express consultation is 99 rubles. We will return the money if you do not like the consultation. Prices are valid until April 20, 2018. To use the service, you need to bind a bank card.
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